isomiRID: a framework to identify microRNA isoforms

نویسندگان

  • Luiz Felipe Valter de Oliveira
  • Ana Paula Christoff
  • Rogerio Margis
چکیده

SUMMARY MicroRNAs (miRNAs) have been extensively studied owing to their important regulatory roles in genic expression. An increasingly number of reports are performing extensive data mining in small RNA sequencing libraries to detect miRNAs isoforms and also 5' and 3' post-transcriptional nucleotide additions, as well as edited miRNAs sequences. A ready to use pipeline, isomiRID, was developed to standardize and automatize the search for miRNAs isoforms in high-throughput small RNA sequencing libraries. AVAILABILITY isomiRID is a command line Python script available at http://www.ufrgs.br/RNAi/isomiRID/.

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عنوان ژورنال:
  • Bioinformatics

دوره 29 20  شماره 

صفحات  -

تاریخ انتشار 2013